POTENCY AND STABILITY STUDIES OF MARKETED PARACETAMOL AND RANITIDINE HCl PREPARATIONS IN BANGLADESH

G. M. S.  Rahman; F.  Ahmed; M. C.  Shill; U. K.  Karmakar; T.   Khaleq; S. M. M.  Alam

doi:10.53808/KUS.2003.5.2.0310-L

Authors

G. M. S. Rahman Department of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
F. Ahmed Pharmacy Discipline, Life Science School, Khulna University, Khulna-9208, Bangladesh
M. C. Shill Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
U. K. Karmakar Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
T. Khaleq Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
S. M. M. Alam Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

DOI:

https://doi.org/10.53808/KUS.2003.5.2.0310-L

Keywords:

Potency, stability, paracetamol, ranitidine, Bangladesh

Abstract

A number of marketed pharmaceutical preparations of paracetamol and ranitidine were analyzed. Potency of the selected products was assayed spectrophotometrically and their various physical parameters (color variation, thickness, weight variation, hardness, friability, disintegration time, dissolution rate) were analyzed according to the official (BP/USP) pharmacopoeial methods. It is evident from the study that most of the brands tested showed Satisfactory results but a few of them failed to meet the specification.