ABORTIC EFFECT OF PAPAYA (Carica Papaya ) IN FEMALE MICE

Abstract

Medicinal plant Carica papaya was used to investigate whether this plant has any effect on abortion. The research work was undertaken to study the abortic effect of papaya in mice. A group of female mice at the age of 4 to 5 weeks were mated with their male counterpart and mating was confirmed by vaginal fluid examination under light microscope following 8 hrs of mating. Female mice were then separated and fed normal diet supplemented with green papaya juice at a rate of 33.33 and 36.66 ml papaya juice per 100 gm normal feed for first five days and then for rest sixteen days of mating, respectively. The experimental female mice showed positive test during first 3 days (pregnancy test) and showed negative test during 14 to 16 days as confirmed by hand palpation. This result suggests that the extract of Carica papaya; an available cheap source in Bangladesh can be used as an alternative drug component for abortion and may also be used as preventive measures of pregnancy. It may be considered that the green papaya juice that used as
abortion aid in the present experiment might be utilized for making abortic pill at low cost. However, identification of actual pill compound and its preparation and marketing needs further research.