Comparison in Nutrient and Bioactivities of Carbohydrate and Ethanol-methanol Extracts of Aegiceras corniculatum (L.) Fruit

Sheikh Julfikar Hossain; Marina Aziz Jyoti; M. Rabiul Islam; G. M. Shamim Ahmed

doi:10.53808/KUS.2024.21.02.1259-ls

Authors

Sheikh Julfikar Hossain Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
Marina Aziz Jyoti Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
M. Rabiul Islam Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
G. M. Shamim Ahmed Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh

DOI:

https://doi.org/10.53808/KUS.2024.21.02.1259-ls

Keywords:

Anthelmintic, Antioxidant, Aegiceras corniculatum, Carbohydrate Fruit, The Sundarbans.

Abstract

Carbohydrate and carbohydrate-based therapeutics are used in treating various diseases. In this study, carbohydrate-enriched (Cah) and ethanol-methanol (1:1; Eth-Met) extracts were prepared from the mangrove fruits of Aegiceras corniculatum in the Sundarbans composed of high content of carbohydrate. The amounts of total carbohydrate, protein, and lipid in Cah extract were 70.4, 7.8, and 2.2% whereas those for Eth-Met extract were 43.9, 8.1, and 2%, respectively. Cah extract had the higher antioxidant activity as it showed significantly (P < 0.05) high total polyphenol content (73.5 mg gallic acid equivalent (GAE)/g extract), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging (at 50 μg extract/mL 85.2%), and total antioxidant capacity (155.5 mg GAE or 120.4 mg ascorbic acid equivalent (AAE)/g extract) than Eth-Met extract. Eth-Met extract showed significantly higher analgesic activity than Cah extract. When mice were orally treated with 250 mg Eth-Met extract/kg body weight showed acetic acid-induced writhing inhibition of 43.1% and needed 14.8 s for response time on a hot plate (55°C). Both Cah and Eth-Met extracts exhibited strong anthelmintic activity with similar concentrations for death time 50 (CDT₅₀) of 11.5 and 10.6 mg/mL respectively for the parasite, Paramphistomum cervi. Therefore, Cah extract can be exploited as a potential source of functional carbohydrates and polyphenols with high antioxidant and anthelmintic activities.

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