HISTOPATHOLOGICAL AND MICROBIOLOGICAL STUDIES ON THE CRUDE EXTRACT OF PERSICARIA STAGNINA AND ITS CHIEF CONSTITUENT STAGNINOL

Authors

  • S.K. Sadhu Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
  • M.U. Ahmed Department of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.
  • B.K. Datta Department of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh.

DOI:

https://doi.org/10.53808/KUS.1999.1.2.295-298-Ls

Keywords:

Histopathology; Persicaria stagnina; Stagninol; Antimicrobial effects

Abstract

Histopathological studies of stagninol, a sesquiterpene isolated from Persicaria stagnina and the crude extract of this plant were carried out on Wistar rats. High dose of the crude extract caused liver necrosis but structural integrity of kidney and spleen remained intact. Low dose of the crude extract and the pure compound stagninol were found to cause no degenerative changes on those organs. Microbiological studies revealed that both the crude extract and stagninol had no inhibitory effect on the growth of a number of bacteria tested.

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References

Ahmed, M., Datta, B.K., Rouf, A.S.S.and Hasan, M.A., 1991. Planta Medica, 57: 503.

Ahmed, M., Sadhu, S.K., Datta, B.K., Kundu, J.K. and Bachar, S.C., 1997. Die Pharmazie, 52(6): 472-475.

Ann Precess, H.H., 1965. A Manual of Histopathologic Technique. Oxford University Press Ltd., London.

Balza, F., Abramowski, Z.G.H.N. and Wiriyachitra, P., 1984. Phytochemistry, 28: 127.

Bauer, A.W., Kirby, W.M.M., Sherris, J.C. and Turck, M., 1966. American Journal of Clinical Pathology, 45(4): 493-496.

Kirtikar, K.R. and Basu, B.D., 1980. Indian Medicinal Plants. B. Singh and M.P. Singh, New Delhi, India.

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Published

26-11-1999

How to Cite

[1]
S. . Sadhu, M. . Ahmed, and B. . Datta, “HISTOPATHOLOGICAL AND MICROBIOLOGICAL STUDIES ON THE CRUDE EXTRACT OF PERSICARIA STAGNINA AND ITS CHIEF CONSTITUENT STAGNINOL”, Khulna Univ. Stud., pp. 295–298, Nov. 1999.

Issue

Section

Life Science