ANTIBACTERIAL AND ANTINOCICEPTIVE ACTIVITY STUDY OF METHANOL  EXTRACT OF MIMOSA PUDICA (L.)

J.A.  Shilpi; S.J.  Uddin; M.  Hossain; M.M.  Sarder

doi:10.53808/KUS.2005.6.1and2.0349-L

Authors

J.A. Shilpi Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
S.J. Uddin Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
M. Hossain Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
M.M. Sarder Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

DOI:

https://doi.org/10.53808/KUS.2005.6.1and2.0349-L

Keywords:

Mimosa pudica, antibacterial activity, antinociceptive activity

Abstract

The methanol extract of Mimosa pudica was studied for its antibacterial activity against twelve pathogenic bacteria. The extract was also studied for its effect on acetic acid induced writhing model in mice. The extract showed good activity against two gram-positive and six gram-negative bacteria but failed to show any activity against Staphylococcus pyogenes, Salmonella typhi, Shigella boydii and Vibrio cholera. The extract exhibited no antinociceptive activity in acetic acid induced writhing test; rather it increased the abdominal constriction or writhing as compared to the control group which is a sign of pain sensation.

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