ANTIBACTERIAL AND ANTINOCICEPTIVE ACTIVITY STUDY OF METHANOL EXTRACT OF MIMOSA PUDICA (L.)

Authors

  • J.A. Shilpi Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
  • S.J. Uddin Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
  • M. Hossain Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh
  • M.M. Sarder Pharmacology Research Laboratory, Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

DOI:

https://doi.org/10.53808/KUS.2005.6.1and2.0349-L

Keywords:

Mimosa pudica, antibacterial activity, antinociceptive activity

Abstract

The methanol extract of Mimosa pudica was studied for its antibacterial activity against twelve pathogenic bacteria. The extract was also studied for its effect on acetic acid induced writhing model in mice. The extract showed good activity against two gram-positive and six gram-negative bacteria but failed to show any activity against Staphylococcus pyogenes, Salmonella typhi, Shigella boydii and Vibrio cholera. The extract exhibited no antinociceptive activity in acetic acid induced writhing test; rather it increased the abdominal constriction or writhing as compared to the control group which is a sign of pain sensation.

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References

Amalraj, T. and Ignacimuthu, S. 2002. Hyperglycemic effect of leaves of Mimosa pudica Linn. Fitoterapia, 73(4): 351-352.

Collier, H.O.; Dinneen, L.C.; Johnson, C.A. and Schneider, C. 1968. The abdominal constriction response and its suppression by analgesic drags in the mouse. British Journal of Pharmacology, 32: 295–310.

Cruickshank, R. 1968. Medical Microbiology: A Guide to Diagnosis and Control of Infection. E. and S. Livingstone Ltd., Edinburgh and London, 888 pp.

Ghani, A. 1998. Medicinal Plants of Bangladesh. Asiatic Society of Bangladesh, Dhaka, 233 pp.

Ikeda, Y.; Ueno, A.; Naraba, H. and Oh-ishi, S. 2001. Involvement of vanilloid receptor VRl and prostanoids in the acid-induced writhing responses of mice. Life Sciences, 69: 2911–2919.

Kirtikar, K.R. and Basu, B.D. 1999. Indian Medicinal Plants. 2nd edition, pp. 915-916.

Murata, T.; Ushikubi, F.; Matsuoka, T.; Hirata, M.; Yamasaki, A.; Sugimoto, Y.; Ichikawa, A.; Ze, Y.; Tanaka, T.; Yoshida, N.; Ueno, A.; Oh-Ishi, S. and Narumiya, S. 1997. Altered pain perception and in-flammatory response in mice lacking prostacyclin receptor. Nature, 388: 678–682.

Raj, P.P. 1996. Pain mechanisms. In: Pain Medicine: A Comprehensive Review. First edn., Mosby-Year Book, Inc., St. Louis, USA, pp. 12–24.

Russel, A.D. and Furr, J.R. 1997. The antibacterial activity of a new chloroxylenol preparation containing ethylenediamine tetraacetic acid. Journal of Applied Bacteriology, 43(2): 253-60.

Whittle, B.A. 1964. The use of changes in capillary permeability in mice to distinguish between narcotic and nonnarcotic alalgesics. British Journal of Pharmacolological Chemotherapy, 22: 246-53.

Yusuf, M.; Chowdhury, J.U.; Yahab, M.A. and Begum, J. 1994. Medicinal Plants of Bangladesh. BCSIR Laboratories, Bangladesh, pp. 87.

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Published

23-11-2005

How to Cite

[1]
J. . Shilpi, S. . Uddin, M. . Hossain, and M. . Sarder, “ANTIBACTERIAL AND ANTINOCICEPTIVE ACTIVITY STUDY OF METHANOL EXTRACT OF MIMOSA PUDICA (L.)”, Khulna Univ. Stud., pp. 35–37, Nov. 2005.

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